Model 2a, Burst Onset and Offset
Although the trend of spike number as a function of input delay for model 2a roughly matches both experimental results and the hypothesized code for stimulus intensity at the granular cell layer (figure 6), the burst offset latencies for the granular cell response of between 80 and 120ms post-EOCD input are nearly twice as long as those that have been observed in vivo (figure 11). Attempts to shorten these offset latencies by increasing the maximum conductances for I-KM and I-KCa inevitably eliminated the sensitivity of burst onset latencies to input delay, as shown in sensitivity curves (figures 19a-iii, 19b-ii).
